Karin Efsen; Efsen Engineering A/S, Vedbæk, Denmark

·   Design of UV lamps

·   UV lamp parameters

·   UV lamp safety considerations

·   Process monitoring

Sonny Joensson; Fusion UV Systems, Inc., Märsta, Sweden

·   Kinetic and mechanisms of photon absorption

·   Classification of photoinitiators

·   Self-initiating monomers

·   Oxygen inhibition and radical scavenging

Sonny Joensson; Fusion UV Systems, Inc., Märsta, Sweden

Sonny Joensson; Fusion UV Systems, Inc., Märsta, Sweden

·   Photopolymerization vs. photocrosslinking - basic

   differences and similarities

·   Free radical vs. cationic mechanisms

·   Hydrophobicity vs. hydrophilicity and hydrogels

·   Photo-crosslinking of commodity polymers and modified

   polymers

Sonny Joensson; Fusion UV Systems, Inc., Märsta, Sweden

Surface Analysis of Medical Plastics

Peter Kingshott; Risø National Laboratory, Danish Polymer Centre, Roskilde, Denmark

·   X-ray photoelectron spectroscopy (XPS)

·   Time-of-flight secondary ion mass spectrometry (XPS)

·   Atomic force microscopy (APM)  

·   Matrix-assisted laser desorption/ionisation time-of-flight

   mass spectrometry (MALDI-TOF-MS)

·   Surface modification by plasma polymerisation

·   Protein adsorption and cell adhesion

Surface Modification Through Plasma Treatment

Anders Larsson; Amersham Biosciences, Uppsala, Sweden

Bringing Together Chemistry and Lamp Systems

Dawn Skinner; Fusion UV Systems Inc., Alton, United Kingdom

·   Issues for using UV curing

·   Selection of bulb to match absorption

·   Selection of bulb to maximise penetration

·   High intensity light

Spectro Radiometry

Mike Stephenson; Solatell Ltd., Croydon, United Kingdom

·   Why monitor a UV process - variables in the UV process

·   UV source variables optics, spectra, power

·   UV source measurement: instrument types, charastiristics

·   UV process measurements in practice; manual, on-line,

   access

UV Adhesives – “Made To Measure” Systems

Jeff Wigham; Wellomer GmbH, Ludwigshafen, Germany

·   How UV-curing adhesives work

·   How to check they are working

·   New developments - reaction indicators

·   New developments - camera recognition

·   New developments - ozone-free cold curing

Process Optimization – Make Sure the Injection Molding Process is as Optimized as Possible!

Peter Bjellheim; Moldflow Scandinavia AB, Mölndal, Sweden

·  The design is the most important for a successful

   process

·  The design team is responsible for the success in the

  production

·  What cannot be measured cannot be managed – the

   importance of keeping  track of what is happening (in

   real  time)

·  High Efficiency – hand in hand with high quality 

Polycarbonate Films for Medical Applications

Hans Braun; Bayer AG, Krefeld, Germany

·   Introduction and overview about product range and

     properties.

·   Processing of polycarbonate films.

·   Customer / processor advantages.

·   Biocompatibility.

·   Applications and examples of PC films In the medical

   field.

Health Impact of PVC Plasticisers in Medical Applications
 

David Cadogan; ECPI, CEFIC, Brussels, Belgium

·   Opinions of expert committees.

·   Risk assessment updates.

·   Latest toxicology information - man monkeys and

   rodents.

·   Alternatives to DEHP.

From Idea to Silicone Reality

Johan Christiansson; Medical Rubber AB, Hörby, Sweden

·  Introduction to liquid silicone rubber,  USA

·  Biocompatibility

·  Design possibilities

·  Typical Applications

Alcohol- and Lipid-Resistant Acrylic-based Plastics for Medical Devices

Peter D. Colburn; CYRO Industries, Orange, USA

·  Acrylic-based materials for medical devices –
   products and applications
·  The progression to alcohol and lipid- resistant acrylic-
    based materials
·  Properties of alcohol and lipid-resistant acrylics vs.
    other transparent materials
·  Determination of practical application performance of
    alcohol and lipid-  resistant acrylics

Regulatory requirements for Marketing Medical Plastics in the United States
 

Carl D’Ruiz, Ciba Specialty Chemicals Corporation, High Point, USA

·  How plastics used in medical devices and  medical

    packaging are regulated by FDA

·   Regulatory and legal requirement for each

·   Providing a platform for helping companies marketing

    medical products in  the United States

HyperDSC, A New Technique for Characterizing Polymers used in Medical Plastics 

Paul Gabbott; PerkinElmer Seer Green, Bucks, United Kingdom

·   Measuring the degree of crystallinity of polymers in a

     unique and accurate way.

·   Discuss the Measurement of very low energy

     transitions, such as the Glass Rubber transition

·   We can begin investigation into the characterization in

     properties of materials when manufactured under fast

     cooling conditions

New Medical Applications of K-Resin Styrene-Butadiene Copolymers

Marc Heerbrant;, Chevron Phillips Chemicals International N.V., Overijse, Belgium

·  Short overview of K-Resin S/B copolymers properties

   and applications in different processes

·  Users of K-Resin styrene-butadiene copolymers in

    medical applications

·  Possibilities of uses of K-Resin styrenics blends in

    medical applications

·  Positioning styrene-butadienne copolymers in the

   transparent polymers market

Cycloolefin-Copolymers in Medical, Pharmaceutical and Diagnostic Applications

Dirk Heukelbach; Ticona GmbH, Kelsterbach, Germany

·   COC grades and applications area  overview
·   Films for medical and pharmaceutical packaging
·   Drug delivery systems
·   Diagnostic devices

Improving Output from Complex Device Assembly Lines
 

Finn Joergensen; Novo Nordisk Engeneering A/S , Hillerød, Denmark 

·  Automated assembly of very complex injection

    devices is a challenge to high machine utilization

·  Machine utilization is typically below 30-40% in

    the pharmaceutical industry

·  Human centered methods based on lean manufacturing

   and total productive maintenance can help develop

   utilization

·  Improvements of 50-100% is possible   

·  Case story showing the methodology

Surface Modification of Polymeric Biomaterials for Improved Understanding of Biocompatibility

Peter Kingshott; Risø National Laboratory, Danish Polymer Centre, Roskilde, Denmark

·  Understanding biocompatibility by advanced surface

    modification and characterisation

·   Functionalisation of polymer surfaces by plasma

    polymerisation

·   Grafting of hydrophilic molecules for repelling protein

    adsorption and cell adhesion

·   Chemical characterisation of surface using  XPS,ToF-

    SIMS, AFM

Inhalation Devices, DPI, pMDI and Nebulizers: a Short up to date Overview

Ola Nerbrink; Novo Nordisk A/S, Hillerød, Denmark

·   Overview of device types

·    Device function

·    Device characteristics

·   Formulations and interaction with

·   Devices

·   Containers and materials used

Tailored Surfaces for Biomolecule Display
 

Henrik M. Pfundheller; Exiqon A/S, Vedbæk, Denmark

·   Functioalisation of surfaces by anthraquinon (AQ) by

     photochemistry

·   Production and applications of AQ-Functionalised

     polymeric microtiterplates and microarray slides

Coatings for Medical Devices

Richard D. Richmond; STS Biopolymers Inc, Henrietta, NY, USA

·   Batch coatings

·  Continuous coatings

·   Hydrophilic coatings

·   Echogenic coatings

·   Drug eluting coatings
 

How to Define and Verify the electrostatic Properties of Plastics Components in the Medical Industry

Reinhold Rutks;Swedish Electro Static AB, Stockholm, Sweden

·   How electrostatics influence the  behaviour of

     unwanted particles

·   Use of static electricity to actively Support the

     production  process

New Developments in the ISO 10993 Series

Scantox A/S; Head of Medical Device Testing , Ll. Skensved, Denmark

·   Which parts are being revised and how far  in the

    process are they?

·   Implication of the revision of existing. parts of the

   standard.

·   New parts of the standard.

·   How will the new developments effect  the biological

    evaluation? 

New Copolyesters for Medical Devices

Inari Seppa; Eastman Company (UK) Ltd. Kirkby, United Kingdom

·  Overview of Eastman Chemical Company

·  Eastman copolyesters: advantages, applications,

   chemistry

·  New copolyester resins for medical devices

·  What is the horizon?

Peek-Optima a Polyaryletherketone Biomaterial for use in Medical Implant Applications

Irene Sinz;  Invibio / Victrex Plc. Thornton Cleveleys, United Kingdom

·  Polymer Advantages/Compound Advantages

·  Peek-Optima

·  Physical Properties

·  Biological Safety – Toxicology

·  Implant Applications/Peek-Optima

PVC – 50 Years in Health Care

John R. Svalander; INSAM SA, Morges, Switzerland,  representing:  ECVM, 4, ave van Nievenhuysen,B-1160 Brussels, BELGIUM

·   Yesterday – why PVC in healthcare and why all the

   debate

·   Today – status of the PVC market in  the health care

   sector

·   Today – PVC industry is pioneering voluntary

    commitments

·   Tomorrow – future of PVC in general and in

    healthcare  specifically

Outsourcing of Production in the Medical Device Industry

Christer Wahlquist; Nolato Medevo AB, Toreskov, Sweden

·   Management of outsourcing.

·   Success factors of outsourcing

·   Advantages/disadvantages of outsourcing

·   Case story – outsourcing from Novo Nordisk to
   Nolato

SEBS Thermoplastic Elastomers in the Medical and Pharmaceutical Industries

Robert L. Wells; Consolidated Polymer Technologies, Inc.,Clearwater, Florida, USA

·   Why SEBS? Structure/property link to important

   applications.

·   Advantages/disadvantages of SEBS based compounds.

·   Current important applications.

·   Possible future products and trends.

Curing Bonded Joints with Confidence

Jeff Wigham; Wellomer GmbH, Ludwigshafen, Germany

·  What are UV curing adhesives?

·  Why UV curing adhesives are used so successfully in

   medical device manufacture

·  Application examples

·  How to check on-line that the process functions

   properly