Advanced Wound Care Experiences are Now Beneficial to Transdermal Drug Delivery Systems

Gerd Büschel

Epurex Films GmbH & Co. KG
Bayershofer Weg 21, DE-29699 Bomlitz, Germany
Tel: +49. 5161 44 3312   Fax: +49. 5161 44 3314

Email: gerd.bueschel.gb@epurex.de

Biography

Born 1959
Graduated mechanical engineer
Sales engineer for Epurex Films since 1995
Responsible for sales + technical support Scandinavia + France;
Project leader for medical plaster business and electronics

Company Profile

Epurex Films – films for ideas

A subsidiary of Bayer MaterialScience AG, Epurex Films has specialized in high-performance technical films for more than 25 years. Our company with 80 employees is located in Bomlitz, Northern-Germany.

Our customers benefit from our global sales network, reliable logistics and our continual investment in research, development, technologies and processes. State-of-the-art blown film extrusion lines are cornerstones of our wide-ranging, variable product portfolio. We are capable of combining various polymers to manufacture special-grade multilayer TPE films with tailored properties.
The high quality of our Platilon® films also comes from selecting and processing appropriate high quality materials which we purchase exclusively from accredited suppliers.

The main markets are medical, automotive, textile and technical industries. We supply also our products for security applications, sport and recreation articles, packaging and building industries.

Typical applications are e.g. waterproof but breathable membranes for modern wound dressings, films for external breast prosthesis, cold/warm therapy gel cushions and orthopedical mattresses.

Abstract

Transdermale systems (TDS) are well known for many years. They become increasingly interesting, because they are very efficiently and simple to handle. Most well-known application here is nicotine plaster. It is based like many other TDS on a very simple system: adhesive with embedded active ingredients + carrier film - similar to a simple tape.

This plaster construction is very limited regarding the usable active substances and the continuous application duration. Further substantial skin irritations are developed in many cases.
                        
The medical field of Advanced Wound Care brought many important developments out in the last 15 years, those in the future also for TDS – will become increasingly important. Examples of these specific properties are:
good adhesion but stress-free removing,
water and microbe barrier but breathable,
long utilization period, connected with high comfort etc.

Further there are new absorption systems (foam among other things), which can be used also as containers for medicines. In the combination of particularly developed materials such as foils, adhesive and foam lies among other things a part of the future solutions for TDS.